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Various issues with muscles and ligaments are the reason for a large number of disability claims. For example, carpal tunnel syndrome and torn ACLs involve ligaments, and piriformis syndrome and whiplash result from damaged or tight muscles.
Social Security has a disability listing covering soft tissue injuries that cause you to lose functional use of a body part and a listing for muscular dystrophy, but to determine whether most of these muscle and ligament conditions are disabling, Social Security will assess how severely they limit your functioning and for how long they are expected to limit your functioning.