Good cholesterol linked to lower MS disability
Research at the University of Buffalo in New York suggests that "good cholesterol" could help patients with multiple sclerosis. Multiple sclerosis is a progressive, inflammatory disease in the brain that attacks the nervous system, causing fatigue and difficulty with cognitive functioning, coordination, walking, and movement. "Good cholesterol" is high-density lipoprotein, HDL, which has positive, protective effects on cardiovascular health, particularly among patients with heart disease.
The study was initiated by Bianca Weinstock-Guttman, M.D., an associate professor of neurology and director of the Jacobs Neurological Institute's Baird Multiple Sclerosis Center at University of Buffalo's Department of Neurology, and first author was Allison S. Drake, MSc, a researcher at JNI. The University of Buffalo is the largest state university in New York and ranks at the top of public universities for research. The results of this research project were presented at the American Association of Neurology in Seattle, Wash.
The research study was an attempt to find a relationship between high-density lipoprotein levels and the level of disability in multiple sclerosis patients. Previous research has established the connection between HDL levels and heart disease, but the relationship with MS had not previously been evaluated. The study looked at 186 multiple sclerosis patients from the New York State Multiple Sclerosis Consortium. The consortium, headed at JNI, is an alliance of NY treatment centers with the intent of assessing clinical characteristics of patients. The average age of the 186 patients was 50. The data included clinical information and HDL levels from the beginning of patients' involvement in the study. After an average of 5 years, researchers compared the initial information with current measures of disability. Disability was measured using the Expanded Disability Severity Score, a physician-reported system.
The results showed a significant association between a patient's level of HDL and disability score. Those patients with greater disability scores had low HDL levels, while those with less disability had higher levels of high-density lipoprotein. The study suggests that high HDL levels may provide a protective effect of anti-inflammatory response in those with multiple sclerosis. The research concluded that more research is recommended, investigating the relationship between HDL levels, treatment and progression of multiple sclerosis.
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The study was initiated by Bianca Weinstock-Guttman, M.D., an associate professor of neurology and director of the Jacobs Neurological Institute's Baird Multiple Sclerosis Center at University of Buffalo's Department of Neurology, and first author was Allison S. Drake, MSc, a researcher at JNI. The University of Buffalo is the largest state university in New York and ranks at the top of public universities for research. The results of this research project were presented at the American Association of Neurology in Seattle, Wash.
The research study was an attempt to find a relationship between high-density lipoprotein levels and the level of disability in multiple sclerosis patients. Previous research has established the connection between HDL levels and heart disease, but the relationship with MS had not previously been evaluated. The study looked at 186 multiple sclerosis patients from the New York State Multiple Sclerosis Consortium. The consortium, headed at JNI, is an alliance of NY treatment centers with the intent of assessing clinical characteristics of patients. The average age of the 186 patients was 50. The data included clinical information and HDL levels from the beginning of patients' involvement in the study. After an average of 5 years, researchers compared the initial information with current measures of disability. Disability was measured using the Expanded Disability Severity Score, a physician-reported system.
The results showed a significant association between a patient's level of HDL and disability score. Those patients with greater disability scores had low HDL levels, while those with less disability had higher levels of high-density lipoprotein. The study suggests that high HDL levels may provide a protective effect of anti-inflammatory response in those with multiple sclerosis. The research concluded that more research is recommended, investigating the relationship between HDL levels, treatment and progression of multiple sclerosis.
Return to:
Other Posts
SSDI — Do You Qualify for Disability?
Social Security Disability and to Qualify for Benefits
Having your attorney file your social security disability or SSI appeal
Social Security Disability and SSI appeals
Social security appeals process
What conditions qualify you for SSI disability?
Social Security Disability review
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