social security disability SSD Disability

A blog by a former social security disability claims examiner about social security disability and SSI Disability issues and questions, but also general, health, and medical news.

Friday, March 28, 2008

Could Genetics be the cause of Lupus

Over a million individuals in the United States alone suffer from lupus, and the majority of those individuals are women (black women are even more likely to suffer from the disease than white women). Lupus is a painful sometimes fatal autoimmune disease that causes the body’s immune system to attack it’s own brain, lungs, joints, skin, blood, and other organs. Lupus attacks may lead to kidney failure, arthritis, and cardiovascular problems.

Researchers have located a group of genes that act as a trigger mechanism to the autoimmune disorder lupus. Lupus is such a complex autoimmune disease that has been difficult to diagnose let alone cure.

Papers published in Nature Medicine and the New England Journal of Medicine pinpoint both new and familiar genetic culprits responsible for developing lupus. A couple of the genes mentioned in the papers were already associated lupus as well as other autoimmune diseases such as type 1 diabetes and rheumatoid arthritis. The excitement came when researchers identified three new genes, in addition to the other known genes.

Why is this so exciting? Identifying these genes may provide better lupus treatments in the short term, and long-range possibilities are very positive. Once researchers, determine what how each gene functions, there may be a way to manipulate them in an effort to at the very least lessen the symptoms of lupus (and possibly other autoimmune disorders). Of course the main goal of researchers is to discover a genetic treatment that will eradicate lupus and other autoimmune disorders if possible.










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