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A blog by a former social security disability claims examiner about social security disability and SSI Disability issues and questions, but also general, health, and medical news.

Thursday, February 7, 2008

Anti-seizure meds and the possible link to suicidal ideations

The FDA began investigating whether or not anti-seizure medications increase the risk of suicide in 2005. The FDA analyzed data from nearly two hundred studies involving eleven popular anti-seizure medications including Neurontin, Depakote, Novartis AG's, and Tegretol. In fact, the FDA believes that all anti seizure medications may potentially increase the risk of suicide.

Anti- seizure medications are used to treat a variety of conditions including migraines, epilepsy, nerve pain disorders, and bipolar disorder.

It is safe to say that millions of people are taking these medications every day, and that some may be at an increased risk of suicidal thought or behavior.

The FDA studies tracked about 28000 patients who were taking anti-seizure medications and 16,000 who took placebo medications. There were four suicides among the 44,000 individuals studied and all four were from the group taking anti-seizure medications.

The increased risk of suicide was higher for medicated individuals no matter what their actual diagnosis was, although individuals with epilepsy had the highest overall suicide risk.

The FDA does not suggest that all individuals who are taking medication stop taking their anti-seizure meds. However it does warn physicians to balance the suicide risk with a patient's need for the medication.

Additionally, the FDA also suggested that patients who were taking anti-seizure medications and their families be made aware of the increased risk of suicidal thoughts or behavior so that the patient's moods could be monitored for changes.



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